The anabolic counterpart to glycolysis is gluconeogenesis, which occurs mostly in the cells of the liver and kidney. In seven of the eleven reactions of gluconeogenesis (starting from pyruvate), the s...The anabolic counterpart to glycolysis is gluconeogenesis, which occurs mostly in the cells of the liver and kidney. In seven of the eleven reactions of gluconeogenesis (starting from pyruvate), the same enzymes are used as in glycolysis, but the reaction directions are reversed. Notably, the ΔG values of these reactions in the cell are typically near zero, meaning their direction can be readily controlled by changing substrate and product concentrations.