Search
- https://chem.libretexts.org/Courses/Fullerton_College/Introductory_Biochemistry/15%3A_Lipids/15.10%3A_Lipid_Details/15.10.03%3A_Fatty_Acid_SynthesisSynthesis of fatty acids occurs in the cytoplasm and endoplasmic reticulum of the cell and is chemically similar to the beta-oxidation process, but with a couple of key differences. The first of these...Synthesis of fatty acids occurs in the cytoplasm and endoplasmic reticulum of the cell and is chemically similar to the beta-oxidation process, but with a couple of key differences. The first of these occur in preparing substrates for the reactions that grow the fatty acid. Transport of acetyl-CoA from the mitochondria occurs when it begins to build up. Two molecules can play roles in moving it to the cytoplasm – citrate and acetylcarnitine
- https://chem.libretexts.org/Courses/Brevard_College/CHE_301_Biochemistry/09%3A_Metabolism_of_Lipids/9.05%3A_Fatty_Acid_SynthesisThe fatty acid synthase system is comprised of seven enzymes linked together with an acyl carrier protein (ACP). As mentioned, this complex is found in the cytoplasm, so its substrates must be as well...The fatty acid synthase system is comprised of seven enzymes linked together with an acyl carrier protein (ACP). As mentioned, this complex is found in the cytoplasm, so its substrates must be as well. The acetyl-CoA in the cytoplasm is primarily derived from the mitochondrial acetyl-CoA via a citrate-malate shuttle that couples deacetylation in the mitochondrion with acetylation in the cytosol.
- https://chem.libretexts.org/Bookshelves/General_Chemistry/Book%3A_Structure_and_Reactivity_in_Organic_Biological_and_Inorganic_Chemistry_(Schaller)/III%3A_Reactivity_in_Organic_Biological_and_Inorganic_Chemistry_1/10%3A_Fatty_Acid_Synthesis/10.01%3A_Overview_of_Fatty_Acid_SynthesisFatty acids are long-chain carboxylic acids. They are metabolically important because they can be used as high-energy fuel sources in the cell. Like gasoline, they contain long hydrocarbon chains, hol...Fatty acids are long-chain carboxylic acids. They are metabolically important because they can be used as high-energy fuel sources in the cell. Like gasoline, they contain long hydrocarbon chains, holding plenty of feedstocks for the formation of strong O-H and C=O bonds.
