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Chemistry LibreTexts

Dihydroxylation

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Dihydroxylation or hydroxylation is the oxidation of an alkene to a glycol. There are two oxidizing agents commonly used for dihydroxylation of alkenes.

1. OsO4
eg:

dihydroxylation 1.png

2. KMnO4
eg:

dihydroxylation2.png

Both reactions are syn additions:

dihydroxylation 3.png

see also ozonolysis, cyclic osmate ester, cyclic manganate ester

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This page titled Dihydroxylation is shared under a All Rights Reserved (used with permission) license and was authored, remixed, and/or curated by Gamini Gunawardena via source content that was edited to the style and standards of the LibreTexts platform.

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