0 - Introduction

The Holland research group has introduced distance mentoring in capillary electrophoresis based on real-time Internet based videoconferencing [1]. By removing distance barriers, this program increases the accessibility of technology as well as knowledge, fosters integrative approaches to scientific research, and bridges geographical gaps. In the previous report, we initiated a research project based on the separation of nonsteroidal anti-inflammatory drugs (NSAIDs) using capillary electrophoresis. For this work, interacting over video was enhanced by clear verbal and nonverbal communication. Following this report, we further supplemented this approach with additional Internet-friendly tutorials, protocols, and learning modules. We have since expanded this work through collaboration with Professor Fred Nesbitt (WVU Ph.D. class of 1982) at Coppin State University in Baltimore, Maryland.

The present collaboration between Coppin State University and West Virginia University entails a more in depth discovery of capillary electrophoresis incorporating fundamental concepts in analytical chemistry including quantitative and qualitative assessment. The tutorial, procedures and learning modules we developed and later implemented with faculty and students at Coppin State University are presented here. These modules may be used with or without a distance partner. The learning modules serve as a guide to understanding the limitations, strengths and flexibility of a capillary electrophoresis system. We suggest the reader makes every effort to complete each learning module before referring to the answer key. Instructions for constructing, assembling and operating a capillary electrophoresis system are also included in this site. When using this material, keep in mind that vendors, manufacturers and suppliers when mentioned are done so as a guide. This is not to be construed as endorsement or recommendation by the authors or Institutions supporting this work. As always, before beginning any work, it is the responsibility of the reader to consult experts in safety and safe use of chemicals and laboratory instrumentation. In some cases, the authors have included advice on safe practices. This information is not to supercede any safety policies or principles in force at other institutions.

[1] LA Holland, S Tomechko, A Oommen, AM Leigh, A Bradford, A Burns, “Real-Time Distance Research with IP network Videoconferencing: Extending Undergraduate Research Opportunities”, Journal of Chemical Education, 81, pp.1224-1228 2004.