Catalytic asymmetric synthesis the synthesis of compound that favors the formation of a specific enantiomer or diastereomer via catalysis synthetic methods. Enantioselective synthesis is a key process in modern chemistry and is particularly important in the field of pharmaceuticals, as the different enantiomers or diastereomers of a molecule often have different biological activity.
- This module presents the recent developments in chiral Lewis acid and Brønsted acid catalysis, especially the systems having the combination of Lewis acids and Brønsted acids. This combined catalytic system has been useful in asymmetric synthesis over the past 20 years.
- Asymmetric carbon-heteroatom bond formation is among the fundamentally important reactions. This module covers the carbon-heteroatom bond-forming reactions using transition-metal-complex as well as the chiral Lewis acid catalyzed protocols.