In the previous chapter, we introduced many of the fundamental concepts that will form the foundation of your understanding of how organic molecules react. Now, we begin our study of organic reactivity in earnest, beginning with the simplest reaction type: the transfer of a proton from an acid to a base. After reviewing some basic ideas about acid-base equilibria with which you are probably already familiar from General Chemistry, we will dive into some very challenging new waters, as we attempt to use our understanding of organic structure to predict how different organic functional groups are likely to react in an acid-base context. Many of the ideas that are introduced in this chapter, though perhaps difficult to grasp as first, will be crucial to understanding not only acid base chemistry but all of the other organic reaction types that we will see throughout the remainder of the text.
Química Orgánica con un Énfasis Biológico de Tim Soderberg (Universidad de Minnesota, Morris)