8: Introduction to Alkyl Halides, Alcohols, Ethers, Thiols, and Sulfides
- Page ID
- 210444
- 8.4: Thiols (Mercaptans)
- Thiols are the sulfur-analogs to alcohols. The major difference is the larger atomic size of sulfur relative to oxygen which creates differences in relative acidity and effectiveness as nucleophiles.
- 8.7: Acidity of Alcohols and Phenols
- Phenols are weakly acidic (pKa = 10) because of their resonance stabilized conjugate base, phenoxide. Alcohols are considered neutral with pKa values similar to water (pKa = 16). The concepts used to predict relative acidity are explained in Chapter 1.
- 8.8: Grignard and Organolithium Reagents
- Many organometallic reagents are commercially available, however, it is often necessary to make then.
- 8.9: Grignard Reagents
- This page takes an introductory look at how Grignard reagents are made from halogenoalkanes (haloalkanes or alkyl halides), and introduces some of their reactions.