Oxidation of Alcohols

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Chromium based oxidations

Typical Oxidants:

Chromium oxidants in aqueous media will oxidize primary alcohols to the corresponding carboxylic acid. The use of PCC, PDC, and Collins Reagent in methylene chloride allows for selective oxidation to the aldehyde.

Tertiary, vinylic alcohols are known to undergo 3,3-sigmatropic rearrangements.

Cr-3,3.png