2: Transition Metal Catalyzed Carbon-Carbon Bond Forming Reactions
- Page ID
- 354339
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- 2.1: Introduction to Transition Metals and Mechanistic Steps
- This chapter introduces concepts of bonding, oxidation state, and electron counting for organometallic transition metal complexes. It also covers fundamental mechanistic steps like oxidative addition, transmetallation, reductive elimination, migratory insertion, and beta-hydrogen elimination.
- 2.2: Pd-Catalyzed Cross Coupling Reactions
- This page focuses on the key carbon-carbon and carbon-heteroatom bond forming reactions catalyzed by palladium including the Stille, Suzuki, Sonogashira, Heck, Tsuji-Trost, and Buchwald-Hartwig reactions.
- 2.3: Olefin Metathesis
- This page covers olefin (alkene) metathesis using catalysts developed by Schrock and Grubbs. The main reaction is ring closing metathesis, while cross metathesis and alkyne metathesis are also covered.
- 2.4: Co-Mediated Ring Forming Reactions
- This page focuses on ring forming reactions promoted by cobalt, specifically the Pauson-Khand reaction to form cyclopentenones and the alkyne cyclotrimerization reaction to yield substituted benzenes.