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Chemistry LibreTexts

11.03 Modeling Replication

  • Page ID
    184334
  • 11.03 Modeling Replication<p><img src="$IMS-CC-FILEBASE$../resources/dnarepmodel_573c8643bbe61.jpg" width="324" height="243" style="float: right; margin: 10px;" id="tme_imgModEnabled" title="" /></p> <p style="line-height: 16.8px;"><span style="font-size: 16px;">Use two ziploc plastic bags to model how complementary strands of DNA attach to template strands during replication.</span></p> <p style="line-height: 16.8px;"><span style="font-size: 16px;">Materials:</span></p> <ul style="line-height: 16.8px;"> <li><span style="font-size: 16px; line-height: 22.4px;">2 ziploc bags</span></li> <li><span style="font-size: 16px; line-height: 22.4px;">scissors</span></li> </ul> <p style="line-height: 16.8px;"><span style="font-size: 16px; line-height: 22.4px;">Procedure:</span></p> <ul style="line-height: 16.8px;"> <li><span style="font-size: 16px; line-height: 22.4px;">Cut the sliding sippers off both bags</span></li> <li><span style="font-size: 16px; line-height: 22.4px;">One zipper represents the template strands of a DNA molecule</span></li> <li><span style="font-size: 16px; line-height: 22.4px;">Cut the other zipper into four smaller pieces and unzip each of them. These represent free nucleotides.</span></li> <li><span style="font-size: 16px; line-height: 22.4px;">Use the pieces to model replication as demonstrated in the animation<a href="http://my.hrw.com/content/hmof/scien...s91/index.html">Replicating DNA</a>.</span></li> </ul> <p><span style="font-size: 16px; line-height: 22.4px;">Analysis:</span></p> <ul> <li><span style="font-size: 16px; line-height: 22.4px;">What are the limitations of this model?</span></li> </ul>