Roadmap Problems in Natural Product synthesis
- Page ID
- 4333
\( \newcommand{\vecs}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)
\( \newcommand{\vecd}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash {#1}}} \)
\( \newcommand{\id}{\mathrm{id}}\) \( \newcommand{\Span}{\mathrm{span}}\)
( \newcommand{\kernel}{\mathrm{null}\,}\) \( \newcommand{\range}{\mathrm{range}\,}\)
\( \newcommand{\RealPart}{\mathrm{Re}}\) \( \newcommand{\ImaginaryPart}{\mathrm{Im}}\)
\( \newcommand{\Argument}{\mathrm{Arg}}\) \( \newcommand{\norm}[1]{\| #1 \|}\)
\( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\)
\( \newcommand{\Span}{\mathrm{span}}\)
\( \newcommand{\id}{\mathrm{id}}\)
\( \newcommand{\Span}{\mathrm{span}}\)
\( \newcommand{\kernel}{\mathrm{null}\,}\)
\( \newcommand{\range}{\mathrm{range}\,}\)
\( \newcommand{\RealPart}{\mathrm{Re}}\)
\( \newcommand{\ImaginaryPart}{\mathrm{Im}}\)
\( \newcommand{\Argument}{\mathrm{Arg}}\)
\( \newcommand{\norm}[1]{\| #1 \|}\)
\( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\)
\( \newcommand{\Span}{\mathrm{span}}\) \( \newcommand{\AA}{\unicode[.8,0]{x212B}}\)
\( \newcommand{\vectorA}[1]{\vec{#1}} % arrow\)
\( \newcommand{\vectorAt}[1]{\vec{\text{#1}}} % arrow\)
\( \newcommand{\vectorB}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)
\( \newcommand{\vectorC}[1]{\textbf{#1}} \)
\( \newcommand{\vectorD}[1]{\overrightarrow{#1}} \)
\( \newcommand{\vectorDt}[1]{\overrightarrow{\text{#1}}} \)
\( \newcommand{\vectE}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash{\mathbf {#1}}}} \)
\( \newcommand{\vecs}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \)
\( \newcommand{\vecd}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash {#1}}} \)
\(\newcommand{\avec}{\mathbf a}\) \(\newcommand{\bvec}{\mathbf b}\) \(\newcommand{\cvec}{\mathbf c}\) \(\newcommand{\dvec}{\mathbf d}\) \(\newcommand{\dtil}{\widetilde{\mathbf d}}\) \(\newcommand{\evec}{\mathbf e}\) \(\newcommand{\fvec}{\mathbf f}\) \(\newcommand{\nvec}{\mathbf n}\) \(\newcommand{\pvec}{\mathbf p}\) \(\newcommand{\qvec}{\mathbf q}\) \(\newcommand{\svec}{\mathbf s}\) \(\newcommand{\tvec}{\mathbf t}\) \(\newcommand{\uvec}{\mathbf u}\) \(\newcommand{\vvec}{\mathbf v}\) \(\newcommand{\wvec}{\mathbf w}\) \(\newcommand{\xvec}{\mathbf x}\) \(\newcommand{\yvec}{\mathbf y}\) \(\newcommand{\zvec}{\mathbf z}\) \(\newcommand{\rvec}{\mathbf r}\) \(\newcommand{\mvec}{\mathbf m}\) \(\newcommand{\zerovec}{\mathbf 0}\) \(\newcommand{\onevec}{\mathbf 1}\) \(\newcommand{\real}{\mathbb R}\) \(\newcommand{\twovec}[2]{\left[\begin{array}{r}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\ctwovec}[2]{\left[\begin{array}{c}#1 \\ #2 \end{array}\right]}\) \(\newcommand{\threevec}[3]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\cthreevec}[3]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \end{array}\right]}\) \(\newcommand{\fourvec}[4]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\cfourvec}[4]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \end{array}\right]}\) \(\newcommand{\fivevec}[5]{\left[\begin{array}{r}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\cfivevec}[5]{\left[\begin{array}{c}#1 \\ #2 \\ #3 \\ #4 \\ #5 \\ \end{array}\right]}\) \(\newcommand{\mattwo}[4]{\left[\begin{array}{rr}#1 \amp #2 \\ #3 \amp #4 \\ \end{array}\right]}\) \(\newcommand{\laspan}[1]{\text{Span}\{#1\}}\) \(\newcommand{\bcal}{\cal B}\) \(\newcommand{\ccal}{\cal C}\) \(\newcommand{\scal}{\cal S}\) \(\newcommand{\wcal}{\cal W}\) \(\newcommand{\ecal}{\cal E}\) \(\newcommand{\coords}[2]{\left\{#1\right\}_{#2}}\) \(\newcommand{\gray}[1]{\color{gray}{#1}}\) \(\newcommand{\lgray}[1]{\color{lightgray}{#1}}\) \(\newcommand{\rank}{\operatorname{rank}}\) \(\newcommand{\row}{\text{Row}}\) \(\newcommand{\col}{\text{Col}}\) \(\renewcommand{\row}{\text{Row}}\) \(\newcommand{\nul}{\text{Nul}}\) \(\newcommand{\var}{\text{Var}}\) \(\newcommand{\corr}{\text{corr}}\) \(\newcommand{\len}[1]{\left|#1\right|}\) \(\newcommand{\bbar}{\overline{\bvec}}\) \(\newcommand{\bhat}{\widehat{\bvec}}\) \(\newcommand{\bperp}{\bvec^\perp}\) \(\newcommand{\xhat}{\widehat{\xvec}}\) \(\newcommand{\vhat}{\widehat{\vvec}}\) \(\newcommand{\uhat}{\widehat{\uvec}}\) \(\newcommand{\what}{\widehat{\wvec}}\) \(\newcommand{\Sighat}{\widehat{\Sigma}}\) \(\newcommand{\lt}{<}\) \(\newcommand{\gt}{>}\) \(\newcommand{\amp}{&}\) \(\definecolor{fillinmathshade}{gray}{0.9}\)Topics required for successful completion are listed under each link.
Carbonyl addition, Carboxylic substitution, Oxidation, Nucleophilic substitution, Alkene addition, Pericyclics
Carbonyl addition, Elimination, Alkene addition, Pericyclics
Carbonyl Addition, Aldol, Carboxyl Substitution, Oxidation, Nucleophilic Substitution, Elimination, Radicals
Aplykurodinone, Danishefsky, 2010
Carbonyl addition, Carboxylic substitution, Oxidation, Nucleophilic Substitution & Elimination
Aza-epothilone B, Danishefsky, 2000
Carbonyl addition, Carboxylic substitution, Nucleophilic Substitution, Bioassay study
Callipeltoside, MacMillan, 2008
Carbonyl addition, Carboxylic substitution, Oxidation, Nucleophilic substitution, Alkene addition
Carbonyl addition, Carboxylic substitution
Carbonyl addition, Carboxylic substitution, Nucleophilic substitution & elimination, Oxidation, Alkene oxidation, Pericyclics
Carbonyl addition, Carboxylic substitution, Nucleophilic Substitution
Carbonyl addition, Carboxylic substitution, Oxidation, Nucleophilic substitution, Alkene addition, Radicals
Carbonyl addition, Conjugate addition, Enolates, Carboxylic substitution, Nucleophilic substitution, Alkene addition, Rearrangements, Radicals
Glucosylceramide, Overkleeft, 2007
Carbonyl addition, Carboxylic substitution, Oxidation, Nucleophilic Substitution & Elimination
Contains a bioassay exercise.
Carbonyl addition, Carboxylic substitution, Aldol & Claisen, A-lpha-alkylation, Conjugate addition, Oxidation, Nucleophilic Substitution & Elimination
Juvenile Hormone 1, Corey, 1968
Carbonyl addition, Phosphorus ylides, Carboxylic substitution, Oxidation, Nucleophilic substitution, Cuprate addition, Alkene addition
Carbonyl addition, Carboxylic substitution, Oxidation, Nucleophilic Substitution & Elimination, Alkene oxidation
Carbonyl addition, Conjugate addition, Carboxylic substitution, Oxidation, Nucleophilic Substitution & Elimination
Carbonyl addition, Aldols, Carboxylic substitution, Oxidation, Nucleophilic Substitution & Elimination, Pericyclics
Perhydrohistrionicotoxin, Corey, 1975
Carbonyl addition, Enolates, Conjugate addition, Carboxylic substitution, Oxidation, Nucleophilic substitution & elimination, Radicals
Carbonyl addition, Aldols, Carboxylic substitution, Oxidation, Nucleophilic Substitution & Elimination, Pericyclics
Carbonyl addition, Carboxylic substitution, Oxidation, Nucleophilic Substitution & Elimination
Carbonyl addition, Carboxylic substitution, Nucleophilic Substitution
Carbonyl addition, Carboxylic substitution
Carbonyl addition, Carboxylic substitution
Carbonyl addition, Carboxylic substitution, Oxidation, Nucleophilic Substitution, Alkene addition
Contains a bioassay exercise.
Serotobenine, Fukuyama & Kan, 2008
Carbonyl addition, Carboxylic substitution, Oxidation, Nucleophilic Substitution & Elimination, Alkene oxidation, Pericyclics
Carbonyl addition, Carboxylic substitution, Oxidation, Nucleophilic Substitution & Elimination, Alkene oxidation
Carbonyl addition, Enolates, Conjugate addition, Carboxylic substitution, Nucleophilic substitution & elimination, Alkene oxidation
Exercise: catalytic cycles in transition metal organometallics.
Carbonyl addition, Carboxylic substitution, Oxidation, Nucleophilic substitution & elimination, Alkene oxidation, Pericyclics, Radicals
Carbonyl addition, Carboxylic substitution, Aldol
Carbonyl addition, Carboxylic substitution, Oxidation, Nucleophilic substitution, Alkene addition, Alkene oxidation, Pericyclics, Rearrangements
Zaragozic acid, Nicolaou, 1994
Carbonyl addition, Carboxylic Substitution, Sulfur ylides, Oxidation, Nucleophilic substitution, Alkene oxidation, Radicals, Organo-transition metal reactions
Nucleophilic Substitution, Alkene addition