Acid chlorides react with ammonia, 1° amines and 2° amines to form amides
- Page ID
- 5956
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Acid chlorides react with ammonia, 1o amines and 2o amines to form amides.
General Reaction
Mechanism
1) Nucleophilic attack by the amine
2) Leaving group is removed
3) Deprotonation
Contributors
Prof. Steven Farmer (Sonoma State University)