1.1: Introduction

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The organic chemistry course is organized as three modules. The chapters referred to below are from L.G. Wade, Jr. Organic Chemistry. 5th ed. Prentice Hall, 2003.

I. MOLECULAR ARCHITECTURE

CHAPTER TOPIC

1: Atomic structure review

Covalent bonding and chemical formulas

Polarity and physical properties of molecules

Lewis formulas, structural isomers, and resonance structures

2: Orbital view of bonding, orbital combinations, hybridization theory

Electron mobility and delocalization in resonance structures

Introduction to functional groups: Alkanes, alkenes, and alkynes

3: Introduction to organic nomenclature: Alkanes and alkyl halides

Structure of alkanes and cycloalkanes,

Conformational analysis

5: Stereochemistry: Molecular architecture in three dimensions

II. MOLECULAR TRANSFORMATIONS: INTRODUCTION TO ORGANIC SYNTHESIS AND REACTION MECHANISMS

CHAPTER TOPIC

4: Energetics of bond breaking and bond formation, reaction mechanisms

Free radical mechanisms

Alkane halogenation as a major tool for alkane functionalization

1 Introduction to ionic mechanisms: Bronsted-Lowry acid-base chemistry

Electron movement in ionic mechanisms

6 / 7 Introduction to Lewis acid-base chemistry and reaction kinetics

Nucleophilic substitution reactions of alkyl halides as a synthetic tool

Elimination reactions and alkene synthesis

III. CHEMISTRY OF COMMON FUNCTIONAL GROUPS

CHAPTER TOPIC

8 / 9 Chemistry of pi-bonds: Alkenes and alkynes

Organometallics, carbon nucleophiles, and their use in organic synthesis

10 Structure and synthesis of alcohols, chemistry of Grignard reagents