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II. Formation of Carbon-Centered Radicals

  • Page ID
    23947
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    The best method for determining the chemoselectivity of two groups in a particular reaction is to compare their reactivity in a substrate containing both. Since this type of testing rarely has taken place, another approach is needed if chemoselectivity in a particular reaction is to be esta­blished from existing data. One alternative is to construct an order of reactivity based on rates of reaction of com­pounds that each contains a single substituent. Such an order can be established from information that exists about rates of reac­tion of Bu3Sn· and (Me3Si)3Si· with compounds that have a single reactive substit­uent.


    This page titled II. Formation of Carbon-Centered Radicals is shared under a All Rights Reserved (used with permission) license and was authored, remixed, and/or curated by Roger W. Binkley and Edith R. Binkley.

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