II. Formation of Carbon-Centered Radicals
- Page ID
- 23947
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The best method for determining the chemoselectivity of two groups in a particular reaction is to compare their reactivity in a substrate containing both. Since this type of testing rarely has taken place, another approach is needed if chemoselectivity in a particular reaction is to be established from existing data. One alternative is to construct an order of reactivity based on rates of reaction of compounds that each contains a single substituent. Such an order can be established from information that exists about rates of reaction of Bu3Sn· and (Me3Si)3Si· with compounds that have a single reactive substituent.