Titrimetry: Analysis of Literature Article
- Page ID
- 282780
\( \newcommand{\vecs}[1]{\overset { \scriptstyle \rightharpoonup} {\mathbf{#1}} } \) \( \newcommand{\vecd}[1]{\overset{-\!-\!\rightharpoonup}{\vphantom{a}\smash {#1}}} \)\(\newcommand{\id}{\mathrm{id}}\) \( \newcommand{\Span}{\mathrm{span}}\) \( \newcommand{\kernel}{\mathrm{null}\,}\) \( \newcommand{\range}{\mathrm{range}\,}\) \( \newcommand{\RealPart}{\mathrm{Re}}\) \( \newcommand{\ImaginaryPart}{\mathrm{Im}}\) \( \newcommand{\Argument}{\mathrm{Arg}}\) \( \newcommand{\norm}[1]{\| #1 \|}\) \( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\) \( \newcommand{\Span}{\mathrm{span}}\) \(\newcommand{\id}{\mathrm{id}}\) \( \newcommand{\Span}{\mathrm{span}}\) \( \newcommand{\kernel}{\mathrm{null}\,}\) \( \newcommand{\range}{\mathrm{range}\,}\) \( \newcommand{\RealPart}{\mathrm{Re}}\) \( \newcommand{\ImaginaryPart}{\mathrm{Im}}\) \( \newcommand{\Argument}{\mathrm{Arg}}\) \( \newcommand{\norm}[1]{\| #1 \|}\) \( \newcommand{\inner}[2]{\langle #1, #2 \rangle}\) \( \newcommand{\Span}{\mathrm{span}}\)\(\newcommand{\AA}{\unicode[.8,0]{x212B}}\)
Assigned Reading:
Karita, S. and Kaneta, T. “Acid-base titrations using microfluidic paper-based analytical devices.” Analytical Chemistry 2014, 86, 12108–12114.
Homework Questions:
- What is a primary standard and how are they commonly used in titrations?
- What primary standard is most often used for the standardization of aqueous bases (e.g., NaOH)? What primary standard is most often used for the standardization of aqueous acids (e.g., HCl)?
- What is a microfluidic device?
- Phenolphthalein is commonly used as an indicator for acid-base titrations. What color is it in solution at each pH listed below?
- <0 b. 0–8.2 c. 8.2–12 d. >13
In-class Questions:
Please read the assigned article and discuss the following with your group members.
- How does the µPAD described overcome the typical disadvantages of acid-base titrations?
- How did the authors have to modify the device to detect acids instead of bases?
- Why did the authors choose phenolphthalein as the indicator for this device? Under what circumstances will this indicator not work?
- One disadvantage of the µPAD is limited precision in terms of the number of significant figures one can report in the concentration. For a traditional titration, what is the limiting factor for the precision of the measurement? For this new µPAD, what is the limiting factor?
- Propose a means by which you could increase the precision of the measurement.
- What dictates the range of concentrations that can be detected by the µPAD?
Contributors and Attributions
- Rebecca Hunter, The Citadel (rhunter1@citadel.edu)
- Sourced from the Analytical Sciences Digital Library