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Chemistry LibreTexts

Grignard Reagents Convert Esters into Tertiary Alcohols

Addition of Grignard reagents convert esters to 3o alcohols.  In effect the Grignard reagent adds twice.

General Reaction

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Example 1

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Mechanism

1) Nucleophilic attack

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2) Leaving group removal

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3)  Nucleophilic attack

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4) Protonation

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Contributors

Prof. Steven Farmer (Sonoma State University)