Grignard Reagents Convert Esters into Tertiary Alcohols
- Page ID
- 5916
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Addition of Grignard reagents convert esters to 3o alcohols. In effect the Grignard reagent adds twice.
General Reaction
Mechanism
1) Nucleophilic attack
2) Leaving group removal
3) Nucleophilic attack
4) Protonation
Contributors
Prof. Steven Farmer (Sonoma State University)