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Chemistry LibreTexts

Acid Chlorides react with carboxylic acids to form anhydrides

Introduction

Acid chlorides react with carboxylic acids to form anhydrides.

General Reaction

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Example 1:
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Mechanism

1)   Nucleophilic attack by the alcohol

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2) Leaving group is removed

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3) Deprotonation

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Contributors

Prof. Steven Farmer (Sonoma State University)